From the scientific paper:
“El glicérido butírico como antibacteriano y estimulador del intestino en broilers” Albéitar: publicación veterinaria independiente, pagg 4,6-7 – Nº. 125, 2009
Autores: Steve Leeson; Teresa García (trad.)
Original title: “Dietary butyrate glycerides – roles as an antibacterial and as a potent stimulator of gut development in poultry. “
Author: Dr Steve Leeson, Department of Animal and Poultry Science, University of Guelph, Guelph, Ontario, Canada.
By combining glycerol with free butyric acid, Silo slr in Florence – Italy has produced what is essentially a “fat” containing up to 85% butyric acid, depending on the site of binding to glycerol. The unique feature of this new industrial process is the removal of any remaining unbound butyric acid, since without these free acid residues there is no smell. As a fat, the butyrate glycerides are protected in the stomach and upper digestive tract and butyric acid will only be released in the small intestine when the normal fat digesting enzymes are activated. Because butyric acid contains 4 carbon atoms as previously described and since it was initially developed for use in diets for baby pigs and other young animals, the local product in Italy is called Baby C4.
(…) One of the commercial challenges of finding alternates to antibiotic growth promoters is health and wellbeing of the broilers. The ever-present threat from coccidiosis and clostridia is a major on-farm issue. In a study we investigated the response of broilers to challenge with coccidiosis. Broilers were fed 1.5kg or 3kg of butyrate/tonne feed either as an encapsulated salt or as the glyceride. Birds were vaccinated for coccidiosis at day of age.
At 14d of age, broilers were each given an oral dose of 50,000 oocysts of mixed culture, and performance measured over the following week (Table 3)
Even though birds were vaccinated, the sudden introduction of a large number of oocysts caused significant mortality in the control group. There was also some mortality in birds fed the butyrate salt, yet no birds died from the groups fed butyrate glycerides throughout the 14-20d evaluation period. Broilers fed 0.3% butyrate glycerides showed over 50% greater growth rate in the week following infection compared to the control birds. These heavier birds also exhibited much reduced ileal, duodenal and cecal coccidial infection scores, suggesting that the oocysts did infect these birds, but the degree of infection was greatly reduced. “